Re: More on Bt-Transgenics and Soil

wytze (geno@zap.a2000.nl)
Sun, 05 Dec 1999 21:56:53 +0100

Charles,
I have a gew remarks on your posting. Since four years I send in questions and
objections to applications for gmo-field trials here in the Netherlands. One standard
objection is that in the applications no research into the effects on soillife of the
gmo-decading plants is mentioned. Since the approval process here is not much
different from other countries, I do not expect the situation to be much better
elsewhere. Therefore I do not think that not only outside but also within the
companies that do trials there is much knowledge about this issue. (I have seen only
from Monsanto some material). Also because, as you say, there is in general still a
lot to be learned about soillife; from what I understood 95% of micro-organisms in
soil are still unknown and their function not understood. Though it is true that
unexpected, adverse effects to soillife may happen through other ways than GE also,
there is good reason to think that the risk for this to occur are higher and will be
harder to combat in GE. Therefore it would be much better in my opinion to not approve
any GE-crop before thorough studies have been performed (preferably during glasshouse
trials), the nature of these studies would, in my opinion, have to be determined in
an open debate with all stakeholders involved.
Wytze de Lange
Biofood Consultancy

Charles Benbrook wrote:

> Mike -- In response to your question -- Yes, different Bt crystals target
> different insects. They also no doubt will behave differently in the soil.
> I doubt anyone outside the companies working on the technology has much of
> an idea what the consequences will be for soil microbial communities of the
> new corn hybrids with Bt expressed through roots at high levels. How could
> they? There is little or no information in the public arena re the
> engineered Bt toxin that will be in the new hybrids, its exact form, and
> levels of expression over time.
>
> I also expect that the manufacturers will, and indeed may have already
> submitted thousands of pages of data/studies that they feel show there will
> be "no problems." Because EPA rules prohibit the agency from publicly
> disclosing this and other data until after a decision has been reached,
> there could be essentially no time between government review/approval and
> widespread marketing. I am sure the grower, land grant and NGO communities
> will press Dow and Pioneer to be much more forthcoming with data than they
> have to be under EPA regulations. Since both companies are trying to not
> follow in Monsanto's footsteps, maybe they will open up the process. If
> they do not, they will be asking for trouble.
>
> My gut feeling is that the scope/degree of change in the soil profile from
> the new corns could be very different from the experimental conditions in
> which past work was carried out. I think many soil ecologists and students
> of soil health feel the same way. Extrapolating safety from past work that
> involved low levels of foliar Bts mixed in soil, to the much higher levels
> of probably partially truncated-activated Bts exuded through roots for
> continuous, extended periods is a huge leap. Stotsky's new work adds a new
> reason to "look before thousands of corn farmers leap,'' as it were.
>
> What might it take for the U.S. EPA to review and act upon this critical
> new GMO technology "correctly" from the perspective of those advocating
> adherence to the precautionary principle? As part of my work with the
> Science and Environmental Network (SEHN) and IATP, I am among a group of
> people working toward at least a preliminary answer to this question.
> Some early thinking follows; we welcome people's reactions and further
> suggestions and dialogue.
>
> The first key goal would be to characterize potential risks (both in the
> soil system and animal/human health, of course) and to establish baselines
> from which potential risk/adverse consequences can be objectively
> monitored. This step entails both the qualitative description of potential
> adverse risk outcomes, and the identification of what amounts to
> mechanisms of action through which bad outcomes might arise, including
> identification of "worst case" combinations of factors that would seemingly
> increase the odds of problems occurring. This later step is key in
> targeting monitoring efforts and to rapidly build confidence that the
> review/approval did cover all the bases.
>
> Next, science/data submitted that supports a prediction that possible
> risks will not amount to much must be critically evaluated. EPA's approval
> will depend largely on whether the agency, and scientists asked to review
> the decision and underlying data, conclude that a persuasive and solid case
> has, in fact, been made.
>
> Last, the agency must insist on there being a credible monitoring system
> and an incremental series of field research activities. It is not
> realistic to expect science to completely foresee the impacts of such a
> technology given the lack of knowledge of what really goes on in soil.
> Accordingly, much greater weight must be assigned to actual infield
> monitoring in the first few years of approval, to make sure the initial
> risk assessment did not completely miss some complex multi-tiered effect.
> The approval also needs to have appropriate "easy out" clauses (i.e.
> conditions) -- if x, y, or z is found in early field research (or other
> required monitoring), the approval is rescinded, period, without EPA having
> to go through a 7 year, multi-million debate with the registrant, as often
> the case with federal pesticide law (under which biotech approvals are
> made). When the registrant/developer has new data showing the problem has
> been fixed, they can always resubmit the technology for a new review.
>
> Both a resistance management and non-target impacts monitoring program
> should be developed and in place, with appropriate safeguards, BEFORE wide
> scale planting. The conditional approval of the new varieties should
> depend upon annual field research/monitoring confirming the projected
> performance of the resistance management plan and lack of "meaningful"
> impacts on non-targets. Increased plantings should lag by a year or two
> the confidence scientists have in the data/knowledge supporting the "no big
> impacts" conclusion.
>
> The EPA's Scientific Advisory panel meets 12/8 to discuss the type of
> research and data needed to project the ecological impacts of Bt-transgenic
> crops on non-target Lepidopterans, soil microbial communities, and other
> non-targets. I hope they spend at least some time considering below the
> ground impacts, and am sure they will given the timely release of the new
> work by Stotsky and colleagues.
>
> chuck
>
>
>
> Charles Benbrook CU FQPA site www.ecologic-ipm.com
> Benbrook Consulting Services Ag BioTech InfoNet www.biotech-info.net
> 5085 Upper Pack River Road IPM site www.pmac.net
> Sandpoint, Idaho 83864
> 208-263-5236 (Voice) 208-263-7342 (Fax)
>
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