In 1995, to get a handle on ATP I used a large piece of paper which evolved
into the a flowchart of the creation, recycling, use, and degradation of
ATP. It also included fatty acid or hormonal influences as I came across
them. PAPS was on this chart, in its own little box, with the products that
are derived from the donated sulfur:
hyaluronic acid in connective tissue, synovial tissue, and vitreous fluid,
keratan sulfate from the cornea and loose connective tissue,
dermatan sulfate from the skin, and
heperan sulfate form basement membranes i.e.. line the GI tract.
Fast forward 18 months.
In 1996 I was pressed to explain why people with Crohn's, fibromyalgia, and
chronic fatigue syndrome were telling me the samples of the original rhea
extract were significantly impacting their lives. I could not explain it.
How could a dried meat product provide pain relief in such varied
conditions? It defied logic.
I had a dream which pointed to the direction. Regressing for a moment to my
college days, totally uninspired by the classroom, I spent countless hours
learning the intricacies of high performance cars. Racing is a euphemism
for "blowing up things" supplying ample opportunity to diagnose, repair, and
gain an intimate understanding of the laws of physics and applied
engineering. The dream was of an IV bag of glucose going into a carburetor.
I woke up and realized that I was looking at the flow of fuel in the body,
the glycolytic pathway that makes ATP, rather than the flow of work,
wherever that was. Even though 20+ years have passed since I torqued
anything, I remembered it was the flow of work that was the significant
pathway determining mechanical efficiency. So, at 2AM I awakened my
engineer husband to verify what I already knew. He was not too impressed I
woke him up to answer such an obvious question. I made the bold assumption
that the glycolytic pathway is just the flow of fuel to the spark plug we
call ATP. It is ATP that actually moves things, so the flow of work has to
derive from ATP. Hence, seemed like the logical flow of work in the body.
Therefore, anything that impacts ATP should impact body efficiency unless
the supporting factors are increased to mitigate the energy drain.
A few other people are addressing the issue. The military, sports medicine,
cardiology (ATP depletion in the heart) recognize the importance. There are
a few references on supplementing with nucleotides and journal letters
calling for the development of laboratory test to quantify ATP status in
patients, but it is only a few voices. One has to understand the importance
of properly identifying the flow of work in the body to understand the
impact decreased ATP can have on body processes. If we don't have the
capacity to measure ATP easily in the body, how can we have the capacity to
determine deleterious effects caused by its decline?
The charts are on my website http:www.rhealiving.com
I have to get ready for a talk on fibromyalgia tomorrow, so part three may
not happen until next week.
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